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1

The mechanism of eukaryotic translation initiation and principles of its regulation

Jackson, Richard J., Hellen, Christopher U. T., Pestova, Tatyana V.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

2

Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29

Hashem, Yaser, des Georges, Amedee, Dhote, Vidya, Langlois, Robert, Liao, Hstau Y., Grassucci, Robert A., Hellen, Christopher U.T., Pestova, Tatyana V., Frank, Joachim

Journal:

Year:

2013

Language:

english

File:

PDF, 4.39 MB

english, 2013

3

Text Segment Length Can Impact Emotional Reactions to Narrative Storytelling

Pham, Hellen, Sanchez, Christopher A.

Journal:

Discourse Processes

Year:

2018

Language:

english

File:

PDF, 1.67 MB

english, 2018

4

Translation Termination and Ribosome Recycling in Eukaryotes

Hellen, Christopher U.T.

Journal:

Cold Spring Harbor Perspectives in Biology

Year:

2018

Language:

english

File:

PDF, 988 KB

english, 2018

5

Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle

Ahrens, Hellen E., Huettemeister, Judith, Schmidt, Manuel, Kaether, Christoph, von Maltzahn, Julia

Journal:

Skeletal Muscle

Year:

2018

Language:

english

File:

PDF, 2.19 MB

english, 2018

6

Extraction of mRNA from Stalled Ribosomes by the Ski Complex

Zinoviev, Alexandra, Ayupov, Rustam K., Abaeva, Irina S., Hellen, Christopher U.T., Pestova, Tatyana V.

Journal:

Year:

2020

Language:

english

File:

PDF, 2.44 MB

english, 2020

7

Viral proteases as targets for chemotherapeutic intervention

Christopher U.T. Hellen, Eckard Wimmer

Journal:

Current Opinion in Biotechnology

Year:

1992

Language:

english

File:

PDF, 699 KB

english, 1992

8

Early identification and preventive care for elevated cardiovascular disease risk within a remote Australian Aboriginal primary health care service

Christopher P Burgess, Ross S Bailie, Christine M Connors, Richard D Chenhall, Robyn A McDermott, Kerin O’Dea, Charlie Gunabarra, Hellen L Matthews, Adrian J Esterman

Journal:

BMC Health Services Research

Year:

2011

Language:

english

File:

PDF, 314 KB

english, 2011

9

Detection of amyloid beta aggregates in the brain of BALB/c mice afterChlamydia pneumoniaeinfection

Ellen Boelen, Frank R. M. Stassen, André J. A. M. van der Ven, Marijke A. M. Lemmens, Hellen P. J. Steinbusch, Cathrien A. Bruggeman, Christoph Schmitz, Harry W. M. Steinbusch

Journal:

Acta Neuropathologica

Year:

2007

Language:

english

File:

PDF, 358 KB

english, 2007

10

10.1038/29703

Pestova, Tatyana V., Borukhov, Sergei I., Hellen, Christopher U. T.

Journal:

Year:

1998

Language:

english

File:

PDF, 355 KB

english, 1998

11

Amalgamated sequences

HELLEN, CHRISTOPHER U. T., CROMBRUGGHE, M. DE, WIMMER, E., SEEGER, M. A., KAUFMAN, T. C.

Journal:

Year:

1989

File:

PDF, 142 KB

1989

12

10.1038/35002118

Pestova, Tatyana V., Lomakin, Ivan B., Lee, Joon H., Choi, Sang Ki, Dever, Thomas E., Hellen, Christopher U. T.

Journal:

Year:

2000

Language:

english

File:

PDF, 249 KB

english, 2000

13

eIF2-dependent and eIF2-independent modes of initiation on the CSFV IRES: a common role of domain II

Pestova, Tatyana V, de Breyne, Sylvain, Pisarev, Andrey V, Abaeva, Irina S, Hellen, Christopher U T

Journal:

The EMBO Journal

Year:

2008

Language:

english

File:

PDF, 355 KB

english, 2008

14

Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes

Pisarev, Andrey V, Kolupaeva, Victoria G, Yusupov, Marat M, Hellen, Christopher UT, Pestova, Tatyana V

Journal:

The EMBO Journal

Year:

2008

Language:

english

File:

PDF, 460 KB

english, 2008

15

Bypassing of stems versus linear base-by-base inspection of mammalian mRNAs during ribosomal scanning

Abaeva, Irina S, Marintchev, Assen, Pisareva, Vera P, Hellen, Christopher U T, Pestova, Tatyana V

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 1.10 MB

english, 2010

16

Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes

Pisareva, Vera P, Skabkin, Maxim A, Hellen, Christopher U T, Pestova, Tatyana V, Pisarev, Andrey V

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 749 KB

english, 2011

17

Small molecule derails translation initiation

Pestova, Tatyana V, Hellen, Christopher U T

Journal:

Nature Chemical Biology

Year:

2006

Language:

english

File:

PDF, 129 KB

english, 2006

18

Translation, interrupted

Pestova, Tatyana V, Hellen, Christopher U T

Journal:

Nature Structural and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 141 KB

english, 2006

19

The fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH

Lomakin, Ivan B, Shirokikh, Nikolay E, Yusupov, Marat M, Hellen, Christopher U T, Pestova, Tatyana V

Journal:

The EMBO Journal

Year:

2005

Language:

english

File:

PDF, 706 KB

english, 2005

20

AP endonuclease paralogues with distinct activities in DNA repair and bacterial pathogenesis

Carpenter, Elisabeth P, Corbett, Anne, Thomson, Hellen, Adacha, Jolanta, Jensen, Kirsten, Bergeron, Julien, Kasampalidis, Ioannis, Exley, Rachel, Winterbotham, Megan, Tang, Christoph

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 337 KB

english, 2007

21

Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing

Unbehaun, Anett, Marintchev, Assen, Lomakin, Ivan B, Didenko, Tatyana, Wagner, Gerhard, Hellen, Christopher U T, Pestova, Tatyana V

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 999 KB

english, 2007

22

Position of the CrPV IRES on the 40S subunit and factor dependence of IRES/80S ribosome assembly

Pestova, Tatyana V, Lomakin, Ivan B, Hellen, Christopher U T

Journal:

Year:

2004

Language:

english

File:

PDF, 255 KB

english, 2004

23

Structure and interactions of the translation initiation factor eIF1

Fletcher, C.Mark, Pestova, Tatyana V., Hellen, Christopher U.T., Wagner, Gerhard

Journal:

The EMBO Journal

Year:

1999

Language:

english

File:

PDF, 297 KB

english, 1999

24

The mechanism of translation initiation on Aichivirus RNA mediated by a novel type of picornavirus IRES

Yu, Yingpu, Sweeney, Trevor R, Kafasla, Panagiota, Jackson, Richard J, Pestova, Tatyana V, Hellen, Christopher UT

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

25

Dehydrogenation of Diamine–Monoboranes to Cyclic Diaminoboranes: Efficient Ruthenium-Catalyzed Dehydrogenative Cyclization

Dr. Christopher J. Wallis, Dr. Hellen Dyer, Dr. Laure Vendier, Dr. Gilles Alcaraz, Dr. Sylviane Sabo-Etienne

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 411 KB

english, 2012

26

Dehydrogenation of Diamine–Monoboranes to Cyclic Diaminoboranes: Efficient Ruthenium-Catalyzed Dehydrogenative Cyclization

Dr. Christopher J. Wallis, Dr. Hellen Dyer, Dr. Laure Vendier, Dr. Gilles Alcaraz, Dr. Sylviane Sabo-Etienne

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 415 KB

english, 2012

27

Internal Initiation of Translation of Bovine Viral Diarrhea Virus RNA

Tatyana V. Pestova, Christopher U.T. Hellen

Journal:

Year:

1999

Language:

english

File:

PDF, 228 KB

english, 1999

28

Maturation of poliovirus capsid proteins

Christopher U.T. Hellen, Eckard Wimmer

Journal:

Year:

1992

Language:

english

File:

PDF, 913 KB

english, 1992

29

Bypassing Translation Initiation

Christopher U.T. Hellen

Journal:

Year:

2007

Language:

english

File:

PDF, 466 KB

english, 2007

30

Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases

Sylvain de Breyne, Jennifer M. Bonderoff, Konstantin M. Chumakov, Richard E. Lloyd, Christopher U.T. Hellen

Journal:

Year:

2008

Language:

english

File:

PDF, 518 KB

english, 2008

31

Ribosome recruitment and scanning: what’s new?

Tatyana V Pestova, Christopher U.T Hellen

Journal:

Trends in Biochemical Sciences

Year:

1999

Language:

english

File:

PDF, 193 KB

english, 1999

32

A satellite RNA of arabis mosaic nepovirus and its pathological impact

YUAN YI LIU, J. IAN COOPER, MARY LOU EDWARDS, CHRISTOPHER U. T. HELLEN

Journal:

Annals of Applied Biology

Year:

1991

Language:

english

File:

PDF, 971 KB

english, 1991

33

IRES-induced conformational changes in the ribosome and the mechanism of translation initiation by internal ribosomal entry

Christopher U.T. Hellen

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Year:

2009

Language:

english

File:

PDF, 1.33 MB

english, 2009

34

Recycling of Eukaryotic Posttermination Ribosomal Complexes

Andrey V. Pisarev, Christopher U.T. Hellen, Tatyana V. Pestova

Journal:

Year:

2007

Language:

english

File:

PDF, 1.40 MB

english, 2007

35

Translation Initiation on Mammalian mRNAs with Structured 5′UTRs Requires DExH-Box Protein DHX29

Vera P. Pisareva, Andrey V. Pisarev, Anton A. Komar, Christopher U.T. Hellen, Tatyana V. Pestova

Journal:

Year:

2008

Language:

english

File:

PDF, 1.77 MB

english, 2008

36

Translation initiation by factor-independent binding of eukaryotic ribosomes to internal ribosomal entry sites

Andrey V. Pisarev, Nikolay E. Shirokikh, Christopher U.T. Hellen

Journal:

Comptes Rendus Biologies

Year:

2005

Language:

english

File:

PDF, 679 KB

english, 2005

37

The Role of ABCE1 in Eukaryotic Posttermination Ribosomal Recycling

Andrey V. Pisarev, Maxim A. Skabkin, Vera P. Pisareva, Olga V. Skabkina, Aurélie M. Rakotondrafara, Matthias W. Hentze, Christopher U.T. Hellen, Tatyana V. Pestova

Journal:

Year:

2010

Language:

english

File:

PDF, 1.07 MB

english, 2010

38

Reconstitution of eukaryotic translation elongation in vitro following initiation by internal ribosomal entry

Tatyana V. Pestova, Christopher U.T. Hellen

Journal:

Year:

2005

Language:

english

File:

PDF, 404 KB

english, 2005

39

Initiation of Protein Synthesis from the A Site of the Ribosome

Joan E Wilson, Tatyana V Pestova, Christopher U.T Hellen, Peter Sarnow

Journal:

Year:

2000

Language:

english

File:

PDF, 292 KB

english, 2000

40

Coupled Folding during Translation Initiation

Tatyana V Pestova, Christopher U.T Hellen

Journal:

Year:

2003

Language:

english

File:

PDF, 106 KB

english, 2003

41

The eIF1A Solution Structure Reveals a Large RNA-Binding Surface Important for Scanning Function

John L. Battiste, Tatyana V. Pestova, Christopher U.T. Hellen, Gerhard Wagner

Journal:

Year:

2000

Language:

english

File:

PDF, 455 KB

english, 2000

42

A Conserved HEAT Domain within eIF4G Directs Assembly of the Translation Initiation Machinery

Joseph Marcotrigiano, Ivan B. Lomakin, Nahum Sonenberg, Tatyana V. Pestova, Christopher U.T. Hellen, Stephen K. Burley

Journal:

Year:

2001

Language:

english

File:

PDF, 1.22 MB

english, 2001

43

Genetics of Poliovirus

Wimmer, Eckard, Hellen, Christopher U. T., Cao, Xuemei

Journal:

Annual Review of Genetics

Year:

1993

Language:

english

File:

PDF, 2.60 MB

english, 1993

44

Reinitiation and Other Unconventional Posttermination Events during Eukaryotic Translation

Skabkin, Maxim A., Skabkina, Olga V., Hellen, Christopher U.T., Pestova, Tatyana V.

Journal:

Year:

2013

Language:

english

File:

PDF, 5.21 MB

english, 2013

45

Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit

Hashem, Yaser, des Georges, Amedee, Dhote, Vidya, Langlois, Robert, Liao, Hstau Y., Grassucci, Robert A., Pestova, Tatyana V., Hellen, Christopher U. T., Frank, Joachim

Journal:

Year:

2013

Language:

english

File:

PDF, 4.53 MB

english, 2013

46

Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29

Hashem, Yaser, des Georges, Amedee, Dhote, Vidya, Langlois, Robert, Liao, Hstau Y., Grassucci, Robert A., Hellen, Christopher U.T., Pestova, Tatyana V., Frank, Joachim

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

47

Direct Contact Between Human Cardiac Fibroblasts and Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Counteracts Changes in Calcium Cycling Induced by Soluble Mediators

Kane, Christopher, Hellen, Nicola, Trantidou, Tatiana, Camelliti, Patrizia, Terracciano, Cesare

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

48

Dendritic BC1 RNA in Translational Control Mechanisms

Huidong Wang, Anna Iacoangeli, Daisy Lin, Keith Williams, Robert B. Denman, Christopher U. T. Hellen and Henri Tiedge

Journal:

The Journal of Cell Biology

Year:

2005

Language:

english

File:

PDF, 2.05 MB

english, 2005

49

Kinetic Analysis of the Interaction of Guanine Nucleotides with Eukaryotic Translation Initiation Factor eIF5B †

Pisareva, Vera P., Hellen, Christopher U. T., Pestova, Tatyana V.

Journal:

Year:

2007

Language:

english

File:

PDF, 195 KB

english, 2007

50

Encyclopedia of Life Sciences || Translation Initiation: Molecular Mechanisms in Eukaryotes

Hellen, Christopher UT

Year:

2001

Language:

english

File:

PDF, 231 KB

english, 2001

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